Bone 06 11 Pdf Bone Osteoblast Bone 06.11 free download as powerpoint presentation (.ppt), pdf file (.pdf), text file (.txt) or view presentation slides online. the document describes the characteristics and microstructure of bone tissue, including the cells (osteoblasts, osteocytes, osteoclasts), bone matrix, and organization of compact and spongy bone. it discusses the roles of osteoblasts in synthesizing bone matrix. The appropriate number of the osteoblasts in the bmu is determined by the differentiation of the precursor bone marrow stem cells into mature osteoblasts, their proliferation with subsequent maturation into metabolically active osteocytes, and osteoblast degradation by apoptosis.
Bone Fractures Pdf Bone Osteoblast Bone tissue cell types osteogenic cells develops into osteoblasts, osteocytes, and osteoclasts. osteoblasts bone building cells regulate blood calcium level osteocytes exchange nutrients and wastes with the blood osteoclasts break down bone tissue (resorption). 2.2 physiology of bone formation bone is composed of support cells, namely, osteoblasts and osteocytes ; remodeling cells, namely, osteoclasts ; and non mineral matrix of collagen and noncollagenous proteins called osteoid , with inorganic mineral salts deposited within the matrix. during life, the bones undergo processes of longitudinal and radial growth, mod eling (reshaping), and remodeling. Osteoclasts • derived from hematopoietic stem cells (monocyte precursor cells) • multinucleated cells whose function is bone resorption • reside in bone resorption pits (howship’s lacunae) • parathyroid hormone stimulates receptors on osteoblasts that activate osteoclastic bone resorption picture courtesy gwen childs, phd. Upon termination of bone formation, mature osteoblasts can flatten to cover the quiescent bone surface as lining cells, die by apoptosis, or surround themselves by bone matrix while.
Bone Tissue Pdf Bone Osteoblast Introduction • bone is a specialised connective tissue composed of calcified extracellular matrix (bone matrix) and bone cells. • the calcified bone matrix makes the bone to be hard, tough and rigid. f functions of bone • bones are the main constituent of adult skeleton & provide solid support for the body. • provide protection to the vital organs e.g. brain in the skull , heart &lungs. The cell responsible for bone resorption, or breakdown, is the osteoclast, which is found on bone surfaces, is multinucleated, and originates from monocytes and macrophages (two types of white blood cells) rather than from osteogenic cells. osteoclasts continually break down old bone while osteoblasts continually form new bone.